Contract

BackgroundThe National Cancer Institutes NCI Rapid Access to Intervention Development program RAID is designed to utilize NCI contract resources to assist extramural investigators with the preclinical and clinical development requirements for drugs and biologics that will be used in clinical trials As part of these new initiative qualified sources is being sought who can produce clinicalgrade vaccinia virus seeds for use in vaccine trials Description of Work To establish two 2 vaccinia viral seed stocks that encode tumor antigens that are expressed at sufficient levels for eventual cGMP production of candidate vaccines for the treatment of cervical carcinoma Preclinical data have shown that both recombinant DNA and vaccinia constructs containing the genegenes of interest can be used as vaccines to generate both specific helper and cytotoxic Tcells CTLs as well as antitumor effects in animal models A synergistic effect is seen when using the DNA and vaccinia constructs in a primeboost regimen The manufacture of the DNA vaccines is already underway and will be used in separate clinical trials Contractor must be able to create two 2 high titer recombinant vaccinia viral seed stocks in fully qualified cell lines that can be eventually used for the manufacture of recombinant vaccinia viruses expressing tumor antigens according to cGMP These viruses will be utilized in Phase I II clinical studies in cervical carcinoma Specific Requirements Include 1 Recombinant vaccinia shuttle vectors harboring the genes encoding the tumor antigens of interest will be supplied to the contractor by SAICNCI 2 The Wyeth Strain of vaccinia virus may be used for generating the recombinant vaccinia virus seed stocks 3 The recombinant vaccinia virus may be created via initial transfection into qualified recipient cells Recombination and plaque selection may be facilitated by thymidine kinase negative qualified HuTK143B cells These cells will be supplied to the contractor by the SAIC 4 Subsequent to multiple rounds of plaque purification confirmation of the expression potency and identity of the cervical tumor antigens will be required Identity testing should include in addition to classical molecular analyses nucleotide sequencing of the transgene and its flanking sequences 5 Potency testing minimally should include immunoprecipitation andor Western Blot analyses of the gene expression Appropriate reagents will be obtained from the RAID Principal Investigator and provided to the Contractor by SAICNCI 6 The purified plaque containing the correct gene sequence and expression profile will be amplified into qualified cells to produce the respective two 2 Master Viral Seed Stocks Contractor Must be Able to Deliver Two 2 vials of viral seed stock containing the respective vectors containing the specific genes of interest All release criteria will be established in advance so that the Contractor will be aware of the exact requirements needed to produce acceptable products Interested companies should describe their capabilities and experience and respond by January 17 2002 to NCIFrederick PO Box B Miller Drive Building 244 Frederick Maryland 21702

• Department/Ind.Agency
• Subtier
• Office

Notice of intent to negotiate a sole source contract for theChannel Islands National Marine Sanctuary CINMS Purpose of proposed acquisition is to provide research vessel technician and coordination services for a oneyear period Proposed contractor possesses unique skills and abilities operating RV XANTU in and around the CINMS Sanctuary near Santa Barbara California Proposed contractor supported CINMS research programs for several years and possesses unique knowledge of XANTU systems and safety requirements Many of these systems are unique to CINMS platform and not otherwise available Questions concerning this acquisition may be directed to Randall Brown at 2065266226 or fax 2065266025 no emails This is a simplified acquisition with an estimated value of less than 100000

• Department/Ind.Agency COMMERCE, DEPARTMENT OF
• Subtier NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION
• Office DEPT OF COMMERCE NOAA

Notice of intent to negotiate a sole source contract with the Monterey Bay National Marine Sanctuary InterAgency Task Forcefor the Monterey Bay National Marine Sanctuary MBNMS Purpose of proposed contract is to design and fabricate eight outdoor interpretive displays for the MBNMS Dispalys will be mounted along the MBNMS Sanctuary shoreline Proposed contractor has been leading public effort to establish a Sanctuary Scenic Trail on the Santa Cruz County coast since 1994 The proposed contractor is uniquely qualified in design and construction of coastal interpretive displays and has designed and erected similar displays in the area New displays wll be prepared for the MBNMS but must be consistent with existing displays along public areas Questions concerning this acquisition may be directed to Randall Brown at 2065266226 or fax 2065266025 no emails This is a simplified acquisition with an estimated value of less than 100000

• Department/Ind.Agency COMMERCE, DEPARTMENT OF
• Subtier NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION
• Office DEPT OF COMMERCE NOAA

Quantity including option quantity Indefinite Quantity Ranges Unit of Issue EA Destination Information UNKNOWNVARIOUS Delivery Schedule 60 DAYS NSN 4330014567159 Filter Element Fluid Manufacturers Code and Part Number if applicable 09LE1 PN SN1121303 70876 PN 20394081 70876 PN DPMDTTK00119 All responsible sources may submit an offerquote which shall be considered Note 26 applies Specifications plans or drawings are not available The proposed procurement contains an option to extend the contract period one or more times at the discretion of the government The total duration base plus option years shall not exceed 5 years This acquisition is for supplies for which the Government does not possess complete unrestrictive technical data therefore the Government intends to solicit and contract with only approved sources under the authority of 10 USC 2304c1 Approved sources are 09LE1 ADVANCED WATER SYSTEMS INC AND 70876 BATH IRON WORKS CORP While price may be a significant factor in the evaluation of offers the final award decision will be based upon a combination of price delivery past performance and other evaluation factors as described in the solicitation Various Increments Solicited FROM TO1 18 19 54 55 89 90 AND UP

• Department/Ind.Agency
• Subtier
• Office

QPL Applies The source for this item must be certified and QPL approved at time of contract award Origin inspection required Critical application item Specification plans or drawings relating to the procurement described are not available and cannot be furnished by the government Delivery schedule 139 days aro Unrestricted The final contract award decision may be based upon a combination of price past performance and other evaluation factors as described in the solicitation Solicitation package must be completed A copy of the solicitation will be available via the DLA Procurement Gateway at httpprogatedapsmilhome or http12321620home on the issue date cited in the RFP From the Gateway homepage select Search RFPs from the lefthand sidebar Then choose the RFP you wish to download RFPs are in portable document format PDF To download and view these documents you will need the latest version of Adobe Acrobat Reader This software is available free at httpwwwadobecom A paper copy of this solicitation will not be available to requestors The solicitation issue date is 010202 Anticipated award date 020102

• Department/Ind.Agency
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PR No YPG01338001559 This solicitation will contain an Indefinite Quantity Contract IQC The solicitation will consist of one base year and four option years Destination inspection required Quantity variance is zero Solicitation will be on and unrestricted basis on other than full and open competition procedures The NSN is as follows 6680010446702 AEQ50Delivery FOB Destination Critical application item Configuration control applies Sources Simmonds Precisions Products 89305 Lockheed Martin Corp 81755 Drawing 16VE002006 REV G DTD 101890 PN 16VE0020062 Specifications or Plans related to the procurement described are not available and can not be furnished by the government on this NSN The final contract award decision may be based upon a combination of price past performance and other evaluation factors as described in the solicitation Effective June 1 1998 in order to receive and award regardless of dollar value you must be registered in the Central Contractor Registration CCR Annual updates to your registration will be required For registration procedures and information please call 18882272423 or visit the World Wide Web at httpccredidsamil A copy of the solicitation will be available via the DLA Procurement Gateway at httpprogatedapsmilhome or http12321620home on the issue date cited in the RFP From the Gateway homepage select Search RFPs from the lefthand sidebar Then choose the RFP you wish to download RFPs are in a portable document format PDF To download and view these documents you will need the latest version of Adobe Acrobat Reader This software is available free at httpwwwadobecom A paper copy of this solicitation will not be available to requestors The solicitation issue date is 9 January

• Department/Ind.Agency
• Subtier
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PR YPG01141001120 NSN 6615012534530 Control Gyroscope ARFP SP044002R1614 Contracting Officer Glenice L DanielChambers8042793158 Issue Date December 31 2001 Closing Date January 31 2002 Subject item is noncommercial The requested delivery schedule cited in the RFP is 200 DARO Subject RFP contains a 100 Option Subject item is sole source to BAE Systems Aircraft Controls Inc cage 07690 PN 47870207 The final contract award decision may be based upon a combination of price past performance and other evaluation factors as described in the solicitation A copy of solicitation will be available via the DLA Procurement Gateway at httpprogatedapsmilhome or http12321620home on the issue date cited in the RFP From the Gateway homepage select Search RFP from the lefthand sidebar Then choose the RFP you wish to download RFPs are in portable document format PDF To download and view these documents you will need the latest version of Adoobe Acrobat Reader This software is available free at httpwwwadobecom A paper copy of the solicitation will not be available to requesters

• Department/Ind.Agency
• Subtier
• Office

The Federal Bureau of Prisons intends to award a NonPersonal services contract for radiology services by a licensed radiologist to provide services to the inmate population at the Federal Correctional Institution FCI Phoenix located at 37900 45th Ave Dept 1680 Phoenix AZ 850277000 All services provided shall be performed in accordance with standards and methods generally accepted within the contractors field of expertise including but not limited to interpretation of xrays providing written andor dictated reports within five 5 working days after reading of the XRays and will include recommendations for further diagnostic testing andor treatment All recommendations will be made to the Clinical Director who will retain professional responsibility for patients referred The Offeror must be a certified Doctor of MedicineDoctor of Osteopathic Medicine degree with specialty training and certification in Radiology The contractor must possess certification to practice in this geographic area Specific services shall be conveniently available to meet the needs of patients as determined by the medical staff eg emergency XRay reading In this case the XRay will be delivered to the Radiologists office for a separate fee Due to the nature of this contract all individuals working within the confines of the institution will be required to submit security clearances Services will be required during the normal work week with a maximum of 1 session per week 1 session 3 hours between the hours of 730AM to 400PM every week excluding federal holidays All offerors are advised that their quotation shall be evaluated in accordance with the evaluation factors as cited in the Request for Quotation The anticipated period of this contract performance will be the base year from Date of Award through 093002 Option Period One 100102093003 Option Period two 100103093004 Option Period three 10010493005 and Option period four 100105093006 This is a unrestrictive procurement It is anticipated that this solicitation will result in a FirmFixed Requirements type contract Solicitation will be available OA 122101 and will be distributed through the General Services Administrations Federal Business Opportunities web site wwwfedbizoppsgov Hard copies of the solicitation document will not be available except in extreme circumstances and only if issuance in this manner is determined to be in the Governments best interest All future information about this acquisition including amendments will be distributed through this site Interested parties are responsible for monitoring this site to ensure that they have the most current information about this acquisition All responsible sources may submit an offer which if timely received shall be considered The NAICS code for this requirement is 621999 cc OSDBU

• Department/Ind.Agency JUSTICE, DEPARTMENT OF
• Subtier FEDERAL PRISON SYSTEM / BUREAU OF PRISONS
• Office WXRO

The USDA Agricultural Research Service in Aberdeen ID has a potential requirement for60 tons normal corn seed per spec 60 tons Low phytate corn seed per specavailable for pickup 12312001 or before We require equal sufficient amounts of grain produced by two corn isohybrids 1 grain produced by a normal hybrid that produces grain with normal levels of total phosphorus thats about 3 to 4 mg total phosphorus per gram of grain and normal levels of phytic acid where phytic acid represents from 75 to 85 of grain total phosphorus 2 grain produced by a Low Phytate isohybrid largely similar in every way to the normal hybrid except in one or a few genes that alter the phytic acid level where the grain again has normal levels of total phosphorus but phytic acid phosphorus is reduced by at least 80 These grain types should be produced under similar production conditions and packaged in 40 lb bags A solicitation is not available for this potential procurement action and the USDA plans to negotiate with the only known source Alder Seed Company Sharpsville IN Interested firms are encouraged to submit proposals based on the above There may be future requirements in the spring of 2002 See number note 22

• Department/Ind.Agency
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Correction The solicitation closing date is extended from December 212001 to January 9 2002 The preferred location for the conference site is within the Washington Metropolitan Area rather than 1 to 3 hours away USAID will provide the computers and printers See attachment 12 for more information

• Department/Ind.Agency AGENCY FOR INTERNATIONAL DEVELOPMENT
• Subtier AGENCY FOR INTERNATIONAL DEVELOPMENT
• Office USAID M/OAA